‘Improving little by little, every day’: the road to Operational Excellence

Every little helps

suggested a figure of 60 — that a chart of their activities would be as unappealingly complicated as a chart of intermediary metabolism. His prediction of the number of motor proteins has turned out to be disturbingly accurate (how did he do it?), though the charts have remained appealing. The significance of all this is that there are movements within cells, and motors responsible for them, th...

Little languages: little maintenance?

So-called little, or domain-specific languages (DSLs), have the potential to make software maintenance simpler: domain-experts can directly use the DSL to make required routine modifications. At the negative side, however, more substantial changes may become more difficult: such changes may involve altering the domain-specific language. This will require compiler technology knowledge, which not...

Uncovering the complexity of Tourette syndrome, little by little.

The aetiology of Tourette syndrome is highly complex and still poorly understood. In this issue, using data from a large, prospective, population-based cohort of children, Mathews et al examine associations of pre- and perinatal exposures with Tourette syndrome and other chronic tic disorders. Their work illustrates the importance of environmental factors in the aetiology of neuropsychiatric co...

Little solution to the little hierarchy problem: A vectorlike generation

Citation Graham, Peter W. et al. " Little solution to the little hierarchy problem: A vectorlike generation. " Physical Review D 81.5 (2010): 055016. Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access...

Results of a Global Study by Arthur D . Little Pathways to Innovation Excellence